Prognosis and prognostic research validating a prognostic model

A panel of national expert reviewers help advise MOCA on the scientific merit and importance of each research proposal, along with a group of consumer advisory review advocates, made up of survivors and caregivers.If you would like to learn more about MOCA’s research funding efforts, contact the MOCA office at (612) 822-0500.

Enter before our closing date, Friday, June 9, 2017. Leaders in the field explore the molecular biology, pathology, risk factors, imaging, treatment and prognosis of this breast cancer.

However, before a risk model is used in clinical practice, the predictive ability of the model should be evaluated.

This process is known as model validation and involves an assessment of calibration (the agreement between the observed outcomes and predictions) and discrimination (the model’s ability to discriminate between low and high risk patients).2 Typically, the model is validated internally (for example, using bootstrapping7 in box 2) or externally using patient data not used for model development (box 1).

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